Nanoparticle Tracking Analysis (NTA) with the Particle Metrix ZetaView® instrument family allows fast and reliable measurement of size, concentration, and Zeta Potential of nanoparticles. In contrast to scatter-based particle detection, fluorescence detection capability of the ZetaView® instrument allows the user to get biochemical information about particles. This increases the resolution and discriminatory power of the data. Furthermore, our recently introduced “Multi Filter Feature” allows Fluorescence Nanoparticle Tracking Analysis performing multi fluorescence with only one laser.  Thus, two different fluorescence dyes can be detected with one wavelength making F-NTA in the ZetaView® instrument more versatile ever since.

Get the newest updates of biomarker detection with NTA:

  • Release of multiple filter upgrade: Double staining with ONE laser!
  • Optimization of labeling strategies
  • Release of FDA 21 CFR part 11 software

Nanoparticle Tracking Analysis (NTA) with the Particle Metrix ZetaView® instrument family allows fast and reliable measurement of size, concentration, and Zeta Potential of nanoparticles in the size range from 10 nm to 2 µm. On basis of the scatter data, the user cannot recognize and distinguish whether the particles are biological vesicles, protein aggregates, inorganic precipitates or simply cell waste. However, the fluorescence detection capability of the ZetaView® instrument allows the user to get biochemical information about particles, thus increasing the resolution and discriminatory power of the data. In this video we describe the cutting-edge measurement technology of the ZetaView® instrument family and present the latest f-NTA results on extracellular vesicle phenotyping using membrane dyes and monoclonal antibodies.