Preparing the sample
As the surface charge of a particle interacts strongly with the charge in its environment, a clean cell is a must. Invisible surfactants may coat the surface and change the ionic charge. During diluting the sample to the measurement concentration, the pH may change. The robust quartz cell guarantees easy cleaning. Internal pumps assist the rinsing process.
Depending on what sizes will be important to analyze, it is necessary to bring the concentration in balance with the camera settings. For known samples the SOP helps, for unknown the software contains a dilution assistant.
Up to the release of ZetaView® 2004, it was not possible to measure zeta potential with a first principle micro-electrophoresis set-up routinely. It was too complicated to align the optics to the stationary layers and to keep the focus sharp over a long time. With ZetaView® this is possible. As the ZetaView® was designed as a portable instrument, automation was a must. This is a strength of the instrument and guarantees repeatability and precision in concentration, size and sub-population analysis of nanoparticles, in scattering and fluorescent mode.
The scatter plot of zeta potential vs size with the new software 8.04.02 tops all that.